Study for People with Cushing’s Syndrome – http://curec.lk/2024gOt
This trial is testing the safety and effectiveness of an investigational drug for the treatment of Cushing’s Syndrome. Under the supervision of qualified physicians, cortisol levels and symptoms of Cushing’s Syndrome will be closely followed along with any signs of side effects. More about the study: The study drug (COR-003) is administered by tablets. There will be 90 participants in this trial There is no placebo used in the trial If you are interested, please find the full study details and eligibility criteria listed here. Eligibility Criteria: Participants must: be at least 18 years old have been diagnosed with endogenous Cushing’s Syndrome by a medical professional (not caused by the use of steroid medications) Participants must not: have been treated with radiation for Cushing’s Syndrome in the past 4 years be currently using weight loss medication have been diagnosed with uncontrolled hypertension, some forms of cancer, adrenal carcinoma, Hepatitis B / C, or HIV Please complete the online questionnaire to check if you’re eligible for the trial. If you’re not familiar with clinical trials, here are some FAQs: What are clinical trials? Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people. Why participate in a clinical trial? You will have access to investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future. Learn why I’m talking about Clinical Trials – http://curec.lk/1Gb4toG
This research study is testing whether a new investigational drug that targets eosinophils (a type of white blood cell) could help patients with COPD (chronic obstructive pulmonary disease) control symptoms and reduce exacerbations (flare-ups) that lead to hospitalizations. The new investigational drug will be compared to oral and inhaled corticosteroids, the current standard of care for COPD.
More about the study:
- The study drug (Benralizumab) is administered by Subcutaneous (under the skin) injection (SC).
- There will be 3794 participants in this trial
If you are interested, please find the full study details and eligibility criteria listed here.
Eligibility Criteria:
Participants must:
- be between 40 – 85 years old
- have been diagnosed by a medical professional as having severe to very severe COPD
- be a current smoker or former smoker
Participants must not:
- be taking any steroid medications by mouth on a regular basis
- have been diagnosed with any type of cancer (except skin or cervical) within the past 5 years.
Please complete the online questionnaire to check if you’re eligible for the trial.
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
This research study is testing whether a new investigational drug that targets eosinophils (a type of white blood cell) could help patients withCOPD (chronic obstructive pulmonary disease) control symptoms and reduce exacerbations (flare-ups) that lead to hospitalizations. The new investigational drug will be compared to oral and inhaled corticosteroids, the current standard of care for COPD.
More about the study:
- The study drug (Benralizumab) is administered by Subcutaneous (under the skin) injection (SC).
- There will be 3794 participants in this trial
If you are interested, please find the full study details and eligibility criteria listed here.
Eligibility Criteria:
Participants must:
- be between 40 – 85 years old
- have been diagnosed by a medical professional as having severe to very severe COPD
- be a current smoker or former smoker
Participants must not:
- be taking any steroid medications by mouth on a regular basis
- have been diagnosed with any type of cancer (except skin or cervical) within the past 5 years.
Please complete the online questionnaire to check if you’re eligible for the trial.
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
New Study for People with Severe Asthma and on Oral Corticosteroids
One of the few treatment options for severe asthma patients who are uncontrolled despite standard treatment is the addition of oral corticosteroids. However, regular intake of these oral corticosteroids can decrease the quality of life for such patients. The purpose of this research study is to see whether the investigational drug can reduce the use of oral corticosteroids in patients with severe asthma.
More about the study:
- The study drug is Benralizumab
- There will be 210 participants in this trial
If you are interested, please find the full study details and eligibility criteria listed here.
Eligibility Criteria:
Participants must:
- be between 18 – 75 years old
- have asthma diagnosed by a doctor at least a year ago
- have been treated with inhaled corticosteroids + LABA for minimum 12 months since today + oral corticosteroids for at least 6 months since today
- have had at least 1 exacerbation (worsening of your asthma that requires medical intervention, emergency room visit, an inpatient hospitalization or a change in medications) in the past year
Participants must not:
- have severe lung disease other than asthma
- have HIV, Hepatitis B or C
Please complete the online questionnaire to check if you’re eligible for the trial.
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
The SPIRE program is looking for people who are taking a cholesterol lowering medication but still have high cholesterol. If you qualify, you might be interested in participating in a research study.
This study evaluates the PCSK9 inhibitor, Bococizumab compared to placebo, in reducing the occurrence of major cardiovascular events, including cardiovascular death, myocardial infarction, stroke, and unstable angina requiring urgent revascularization, in high risk subjects who are receiving background lipid lowering therapy and have cholesterol laboratory values of LDL-C >/= 70 mg/dL or non-HDL-C >/= 100 mg /dl
The full study details and eligibility criteria are listed here.
Please complete the online questionnaire to check if you’re eligible for the trial.
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
Requesting Healthcare Records
By Barby Ingle
(excerpt from The Pain Code Book)
One thing I have learned over the years is how important it is to keep a copy of all of your medical records. My insurance companies have tried to force me into “step therapy” and without my medical records it would have been very difficult and long process to get through. I save my providers time as well, when I can fill out the insurance forms for appeals and send them over for the doctor to just review and forward on. In 2012, I was again faced with a step therapy request from my insurance company that came in the form of a written letter. They said, “If you have already tried the other medications with fail, your doctor should have done the Medform 3500, which is completed and sent into a clearing house.”
There is voluntary reporting form 3500, and the 3500A that is for issues that are mandatory to report. I went online and found the form and directions on the FDA government website. [1] Once I filled in all of the information, I copied it, attached the pertinent records, and sent it to my doctor. He finished completing it (using the records I attached) and signed and faxed it in. A few days later I called the insurance company to let them know I had a Medform 3500 on file. Within a few hours of calling my insurance company to let them know my medication was ready to be picked up from the pharmacy and they dropped the step therapy requirement for me.
You can typically obtain your medical records by writing out a request or filling out a premade form from the provider.
Your record request should include the following: [2]
- Date of the request
- Full Name
- Date of birth
- Social security number
- Telephone number
- Name, address, fax, and telephone number where the records are to be sent
- Purpose of the request (typically, there can be a charge for ordering your records). Each state has different laws on how much can be charged, for instance, there is a law in Arizona that if the records are being used for continuing care, the provider cannot charge you
- Specific items or dates of service needed
- Any restrictions on the request
- Date this authorization expires (authorizations must be less than one year old)
- A statement in writing indicating that the patient knows that they have a right to revoke this authorization at any time
- A statement indicating that the patient knows that signing this authorization is not a condition of obtaining treatment
- A statement indicating that the patient understands the potential for the protected health information to be re-disclosed by the recipient and no longer protected
- The signature of the patient or, if the patient is a child, the parent or guardian. If signed by a personal representative, a description of his/her authority to act for the individual and a copy of the document giving that authority. Records are not usually released while a patient is still hospitalized because they are incomplete
If you are in a state that is able to charge for copies of your medical records, you may save some money asking for specific documents or all recent major reports rather than requesting the entire record. Most of my requests have been filled with in 5 to 10 days but it may take up to one month. If you have not heard back in 30 business days, you may want to call or send a written follow up request. A few providers are offering your records online and others may provide it to you in electronic form if you provide them a flash drive.
Check with each provider as to the method they prefer. Some providers will fax medical records and some will only fax them to another healthcare provider in cases of immediate emergency. Your records are the physical property of the provider, however, the patient controls the release of the information contained in their record. In addition, if you are moving away from your provider, you may request your entire file so that you may provide it to the next provider who will be taking over your care. Providers must keep a copy of your records for a particular amount of years. In some states it is seven, others it is ten years, although most providers keep them longer.
[1] www.fda.gov/Safety/MedWatch/HowToReport
[2] Sample in The Pain Code Journal
NEW ASTHMA TREATMENT AVAILABLE IN CLINICAL TRIAL
If you have Mild or Moderate Asthma and you’re looking for new treatment options, this clinical trial may be right for you.
This study is for patients who have mild or moderate asthma and are using a reliever inhaler. If approved, it is hoped that the study drug will improve your lung function and overall symptoms of asthma.
More about the study:
- The study drug (Lebrikizumab ) is administered by Subcutaneous injection (SC).
- This trial is 22 weeks long, requiring 9 visits and 0 overnight stays
If you are interested, full study details and eligibility criteria are listed here.
Eligibility Criteria:
Participants must:
- between 18 – 75 years old
- be diagnosed with asthma for more than 1 year
- be willing to attend 9 study visits over a 22 week period of time
Participants must not:
- have used corticosteroids in the last 4 weeks
- have any other lung diseases (like COPD )
- be a current smoker
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
Please complete the online questionnaire to check if you’re eligible for the trial.
Biogen Idec is running a registry for researchers to advance their knowledge of early Alzheimer’s Disease. If you’re having memory problems or are worried you’re at risk of early Alzheimer’s, you can play an important role in improving our understanding of the disease. You will have the opportunity to learn about and take part in local studies looking at new treatment options. You will also receive some reimbursement for your time.
More about the registry:
- There will be 14000 participants in this registry
- This registry will take place over two years requiring no visits or overnight stays
- This registry is taking place nationwide and you can complete it from the comfort of you own home.
If you are interested, the full study details and eligibility criteria are listed here.
Eligibility Criteria:
Participants must:
- be between 50 – 85 years old
- be willing to answer questionnaires periodically over a 2 year block of time
- be concerned that you are at risk for developing early Alzheimers have difficulty with memory or thinking skills
Participants must not:
- already be diagnosed with Alzheimers Disease
- have had events of stroke, epilepsy, or Parkinson’s Disease Please complete the online questionnaire to check if you’re eligible for the trial.
ADDITIONAL INFO ON THE REGISTRY
If you agree to participate in the registry, you will be asked to complete an online questionnaire to assess how you understand, remember, and communicate information. This questionnaire will be repeated every 3 – 6 months. You will also be asked to take a brief 10 – 15 telephone call, which will be repeated every 6 months. The registry team may use your answers to see if you may qualify for another clinical research study. If you are interested in participating, we will ask for your permission to send your contact details to the study center. After you speak with someone at the study center, you can decide whether or not you want to participate in the study.
Please complete the online questionnaire to check if you’re eligible for the registry.
RHEUMATOID ARTHRITIS CLINICAL TRIAL SEEKING PARTICIPANTS
Rheumatoid Arthritis is a chronic inflammatory disorder affecting small joints in the hands and feet that affects about 1.5 million people in the United States today.
There is a clinical study available to those with Rheumatoid Arthritis, where the purpose of the study is to compare the proposed biosimilar study drug rituximab (GP2013) against a standard approved treatment rituximab (Rituxan®) to see if the study drug is as safe and effective in treating rheumatoid arthritis.
More about the study:
- The study drug (GP2013 and Rituximab) is administered by IV Injection (IV).
- At least 174 people have already taken this drug in clinical trials
If you are interested, the full study details and eligibility criteria are listedhere.
Eligibility Criteria:
Participants must:
- be at least 18 years old
- have been diagnosed with rheumatoid arthritis for at least 6 months
- have had inadequate response or intolerance to DMARDs (disease-modifying anti-rheumatic drugs) and 1 – 3 anti-TNF (tumor necrosis factor) therapies
- have received methotrexate for at least 4 months with 25 mg/week as the maximal dose
Participants must not:
- have significant liver disease, or congestive heart failure
- be taking a high potency of opioid analgesics (e.g. methadone, hydromorphone, morphine)
Please complete the online questionnaire to check if you’re eligible for the trial.
If you’re not familiar with clinical trials, here are some FAQs:
What are clinical trials?
Clinical trials are research studies to determine whether investigational drugs or treatments are safe and effective for humans. All new investigational medications and devices must undergo several clinical trials, often involving thousands of people.
Why participate in a clinical trial?
You will have access to new investigational treatments that would be available to the general public only upon approval. You will also receive study-related medical care and attention from clinical trial staff at research facilities. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.
What do you say to others when you live with an invisible illness/disability – Chronic Pain
Barby Ingle- Excerpt from RSD in Me©
You can never take back information once it is shared but you can always wait to let people know later. If you choose to disclose that you have chronic pain, decide when and how to do so. If there is time to prepare ahead of time, it is a good idea. Take time to think about different situations and how you wish to handle them. Many people feel it is not their place to ask about your physical conditions, but knowing about chronic pain and your disease specifically would help them understand where you are coming from with your thoughts and actions. When you are deciding to disclose your chronic pain and limitations, make the decision whether or not to let others know about your invisible disability.
I know a chronic pain patient who liked a neighbor and was interested in dating him. He often helped around her house with handyman projects, and she would see him out on his porch and go out and talk to him. Eventually, he asked her out, and they had a great time. Over the next few months they had dates scheduled but she ended up canceling a lot of them. She was just in too much pain. He began to think she was not interested in him and started to pull away. Friends encouraged her to tell him about chronic pain and what she is going through. She did, and he stuck around for a while. In the end it did not work out, but they remained friends and it helped her see that you can still have a social life despite the chronic pain. If you’re in this or another social situation you should think about the following when deciding to disclose your chronic pain and how it affects your everyday life. Are you able to participate in the activities at hand using your coping skills and tools? Do you need accommodations? Are you able to perform the activity safely if you choose not to disclose? Secondly, do you think they will react in a way appropriate for the environment you are in? If you are not sure, you may want to wait until you are in a private setting. If the situation becomes an intimate relationship, it is important to share even if it means losing the person. It is not fair to them or yourself to keep information back. If your disability is in remission or typically under control, is there a reason to disclose? Possibly the education you give them may help someone else they meet along the way. It is possible that flare-ups on your part may keep you from future activities. Finally, how will you address misconceptions about your disability when you disclose? Some people do not believe in treating pain with narcotic medications or have a bad experience with someone else in their life with chronic pain. Having them not understanding can lead to a divide. Also, not telling others is not an option if you are in a situation that can cause others harm. For instance, when getting on a plane, you cannot have the exit row. If assigned by mistake, notify the flight crew.
When choosing situations and activities where you do not want to disclose your disability, take time to carefully analyze the kind activities you are able to do and plan accordingly. Remember, you can always reveal more information later as needed. The following are some of the risks and benefits of letting others know about your invisible disability.
Risks
- Many chronic pain patients are seen as a drug or attention seeker, or as mentally unstable.
- You may face discrimination, subtle or direct, from work, friends and caretakers.
- You may face envy or resentment for receiving special treatment from the others in your life, especially with children.
- You may not be asked to participate in the event or future activities, if the other person does not understand.
- You will have to give up your privacy to receive help bathing, eating and corresponding with others.
Benefits
- Letting others know about chronic pain and what you are living with daily can give you a sense of purpose and support for yourself and others in your life.
- Openness with your doctors, family and public can create understanding for others with invisible disabilities.
- You may be an ambassador for others with disabilities as a public educator, mentor or on a personal level.
- Your abilities, attitudes and success may counteract any discrimination. I think, if I keep doing what I can, they will eventually see. Even if they don’t get it, you can still be successful.
Barby Ingle- Excerpt from RSD in Me©
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